COMPÓSITOS À BASE DE ALGINATO E ÓXIDO DE GRAFENO EM TÊXTEIS MÉDICOS: APLICAÇÕES, DESAFIOS E PERSPECTIVAS FUTURAS
DOI:
https://doi.org/10.54899/dcs.v23i86.4310Palavras-chave:
Alginato, Óxido de Grafeno, Compósitos, Têxteis Médicos, BiopolímerosResumo
Têxteis médicos são materiais projetados para uso em aplicações na área da saúde, podendo ser fabricados a partir de diversas matérias-primas. O alginato é um biopolímero bastante estudado e utilizado na produção de fibras, filmes, hidrogéis, scaffolds e curativos para o desenvolvimento de têxteis médicos. Materiais derivados de biopolímeros podem apresentar baixa resistência à tração e à compressão, mas a adição de outros materiais, como o óxido de grafeno, pode melhorar essas propriedades, bem como conferir atributos adicionais. O óxido de grafeno vem sendo estudado para aplicações em têxteis médicos devido às suas múltiplas propriedades, como alta resistência mecânica, boa biocompatibilidade e propriedades antimicrobianas, podendo ser ainda associado a outros materiais com o objetivo de funcionalizá-los. Este trabalho teve como objetivo reunir as principais informações sobre as aplicações atuais, os desafios e as perspectivas futuras do uso de alginato e óxido de grafeno na produção de compósitos para têxteis médicos.
Downloads
Referências
AHMAD, Farooq et al. Graphene and its derivatives in medical applications: A comprehensive review. Synthetic Metals, v. 304, p. 117594, 2024.
CHAUHAN, Narendra Pal Singh et al. Functionalization of graphene oxide and its applications in tissue engineering and regenerative medicine. Biomaterials Advances, v. 178, p. 214421, 2026.
DEL GAUDIO, Pasquale et al. In situ gelling alginate-pectin blend particles loaded with Ac2-26: A new weapon to improve wound care armamentarium. Carbohydrate Polymers, v. 227, p. 115305, 2020.
GRAND VIEW RESEARCH. Alginate Market Size, Share & Trends Analysis Report by Type, By Product, By Application, By Region, And Segment Forecasts, 2021 - 2028. Disponível em: https://www.grandviewresearch.com/
industry-analysis/alginate-market. Acesso em: 09 de outubro de 2025.
GRAND VIEW RESEARCH. Medical Textiles Market Size, Share & Trends Analysis Report by Type, By Application, By Region, And Segment Forecasts, 2023 - 2030, 2023. Disponível em: https://www.grandviewresearch.com/industry-analysis/medical-textiles-market. Acesso em: 09 de outubro de 2025.
IQBAL, Yasir; AMIN, Faheem; GILANI, Noor ul Hudda. Freeze-gelated sodium alginate incorporated GO hydrogel membrane fabrication, thermal and mechanical studies. Materials Letters, v. 351, p. 135060, 2023.
ISLAM, Md Monirul; ISLAM, Md Hasibul; MONDAL, Md Ibrahim H. Alginate fibres—synthesis, structure, and applications. Technical Organic and Inorganic Fibres from Natural Resources, p. 121–144, 2025.
JAHANDIDEH, Arash; ASHKANI, Mojdeh; MOINI, Nasrin. Biopolymers in textile industries. In: Biopolymers and their Industrial Applications. Elsevier, p. 193–218, 2021.
JAHANI, Afsaneh et al. Incorporating insulin into alginate-chitosan 3D-printed scaffolds: A comprehensive study on structure, mechanics, and biocompatibility for cartilage tissue engineering. Carbohydrate Polymer Technologies and Applications, v. 9, p. 100696, 2025.
KHAN, Safia; KHAN, Mariam. Applications of Sodium Alginate in Science. Sodium Alginate-Based Nanomaterials for Wastewater Treatment, p. 161–182, 2023.
KUMAR, Brijesh; SINGH, Narendra; KUMAR, Pramendra. A review on sources, modification techniques, properties and potential applications of alginate-based modified polymers. European Polymer Journal, v. 213, p. 113078, 2024.
LEKHAVADHANI, Sundaravadhanan et al. Recent progress in alginate-based nanocomposites for bone tissue engineering applications. Colloids and Surfaces B: Biointerfaces, v. 250, p. 114570, 2025.
LI, Chenxi et al. Sodium alginate/chitosan composite scaffold reinforced with biodegradable polyesters/gelatin nanofibers for cartilage tissue engineering. International Journal of Biological Macromolecules, v. 285, p. 138054, 2025.
LI, Jiwei et al. Adsorption of lysozyme by alginate/graphene oxide composite beads with enhanced stability and mechanical property. Materials Science and Engineering: C, v. 89, p. 25–32, 2018.
LIU, Jie et al. Sodium alginate/cellulose nanocrystal fibers with enhanced mechanical strength prepared by wet spinning. Journal of Engineered Fibers and Fabrics, v. 14, 2019.
MA, Jianhua et al. Ca 2+ crosslinking sodium alginate/graphene oxide composite fiber with enhanced mechanical strength and fire retardancy. The Journal of The Textile Institute, v. 114, n. 7, p. 1070–1077, 2023.
MA, Rongxiu et al. Nanocomposite sponges of sodium alginate/graphene oxide/polyvinyl alcohol as potential wound dressing: In vitro and in vivo evaluation. Composites Part B: Engineering, v. 167, p. 396–405, 2019.
MANSOURI, Negar et al. Advancing fabrication and properties of three-dimensional graphene–alginate scaffolds for application in neural tissue engineering. RSC Advances, v. 9, n. 63, p. 36838–36848, 2019.
MARRELLA, A. et al. Enhanced mechanical performances and bioactivity of cell laden-graphene oxide/alginate hydrogels open new scenario for articular tissue engineering applications. Carbon, v. 115, p. 608–616, 2017.
MARTÍ, Miguel et al. Calcium alginate/graphene oxide films: Reinforced composites able to prevent Staphylococcus aureus and methicillin-resistant Staphylococcus epidermidis infections with no cytotoxicity for human keratinocyte HaCaT cells. European Polymer Journal, v. 110, p. 14–21, 2019.
MUHAMMAD, Marinah et al. Synthesis of Sodium Alginate Graphene Oxide-Silver Film for Antibacterial Activity. IOP Conference Series: Earth and Environmental Science, v. 596, n. 1, p. 012041, 2020.
NIE, Ling et al. Effects of surface functionalized graphene oxide on the behavior of sodium alginate. Carbohydrate Polymers, v. 117, p. 616–623, 2015.
PRIYADARSINI, Subhashree et al. Graphene and graphene oxide as nanomaterials for medicine and biology application. Journal of Nanostructure in Chemistry Springer Medizin, 2018.
PUNNOY, Pornchanok et al. Novel theranostic wounds dressing based on pH responsive alginate hydrogel/graphene oxide/levofloxacin modified silk. International Journal of Pharmaceutics, v. 661, p. 124406, 2024.
RASLAN, Ahmed et al. Graphene oxide and reduced graphene oxide-based scaffolds in regenerative medicine. International Journal of Pharmaceutics, v. 580, p. 119226, 2020.
RAUS, Raha Ahmad; NAWAWI, Wan Mohd Fazli Wan; NASARUDDIN, Ricca Rahman. Alginate and alginate composites for biomedical applications. Asian Journal of Pharmaceutical Sciences, v. 16, n. 3, p. 280-306, 2021.
SAHOO, Deepti Rekha; BISWAL, Trinath. Alginate and its application to tissue engineering. SN Applied Sciences, v. 3, n. 1, p. 1–19, 2021.
SHANKAR, Krishna et al. A review on antimicrobial mechanism and applications of graphene-based materials. Biomaterials Advances, v. 150, p. 213440, 2023.
SHARIATI, Aref et al. Graphene-Based Materials for Inhibition of Wound Infection and Accelerating Wound Healing. Biomedicine & Pharmacotherapy, v. 158, p. 114184, 2023.
SHEN, C.; OYADIJI, S. Olutunde. The processing and analysis of graphene and the strength enhancement effect of graphene-based filler materials: A review. Materials Today Physics, v. 15, p. 100257, 2020.
SHIRVAN, Anahita Rohani; NOURI, Alireza. Medical textiles. In: Advances in Functional and Protective Textiles. Elsevier, p. 291–333, 2020.
SINDI, Amal M. Applications of graphene oxide and reduced graphene oxide in advanced dental materials and therapies. Journal of Taibah University Medical Sciences, v. 19, n. 2, p. 403–421, 2024.
SINGH, Harvinder et al. Graphene for next-generation technologies: Advances in properties, applications, and industrial integration. Results in Engineering, v. 27, p. 106865, 2025.
SUNDAR, L. Syam; ASHRAF, Muhammad Waqar. Synthesis and characterization methods of graphene oxide nanomaterial for biomedical and toxicity applications: A comprehensive review. Inorganic Chemistry Communications, v. 174, p. 113936, 2025.
TIRKEY, Akriti et al. Alginate-based nanocomposite hydrogels for antimicrobial and antibiofilm applications. In: Functional Nanocomposite Hydrogels. Elsevier, p. 363–385, 2023.
UMOREN, Saviour A.; SOLOMON, Moses M.; SAJI, Viswanathan S. Alginate and its derivatives. In: Polymeric Materials in Corrosion Inhibition. Elsevier, p. 271–286, 2022.
VALOROSI, Filippo et al. Graphene and related materials in hierarchical fiber composites: Production techniques and key industrial benefits. Composites Science and Technology, v. 185, p. 107848, 2020.
VARAPRASAD, Kokkarachedu et al. Alginate-based composite materials for wound dressing application: A mini review. Carbohydrate Polymers, v. 236, p. 116025, 2020.
XIE, Feng et al. Alginate foam gel modified by graphene oxide for wound dressing. International Journal of Biological Macromolecules, v. 223, p. 391–403, 2022.
XIE, Fengwei; GAO, Chengcheng; AVÉROUS, Luc. Alginate-based materials: Enhancing properties through multiphase formulation design and processing innovation. Materials Science and Engineering: R: Reports, v. 159, p. 100799, 2024.
YOUSEFIASL, Satar et al. Chitosan/alginate bionanocomposites adorned with mesoporous silica nanoparticles for bone tissue engineering. Journal of Nanostructure in Chemistry, v. 13, n. 3, p. 389–403, 2023.
YUN, Yajing et al. Facile synthesis of Ca2+-crosslinked sodium alginate/graphene oxide hybrids as electro- and pH-responsive drug carrier. Materials Science and Engineering C, v. 108, 2020.
ZHANG, Miao; ZHAO, Xia. Alginate hydrogel dressings for advanced wound management. International Journal of Biological Macromolecules, v. 162, p. 1414–1428, 2020.
ZHANG, Qianyu et al. “Bamboo-like” strong and tough sodium alginate/polyacrylate hydrogel fiber with directional controlled release for wound healing promotion. Carbohydrate Polymers, v. 347, p. 122761, 2025.
Zin, Farah Amanina Mohd et al. Synthesis of Sodium Alginate Graphene Oxide-Silver Film for Antibacterial Activity. IOP Conference Series: Earth and Environmental Science, v. 596, n. 1, p. 012041, 2020.
Downloads
Publicado
Como Citar
Edição
Seção
Licença
Copyright (c) 2026 Revista DCS
Este trabalho está licenciado sob uma licença Creative Commons Attribution-NonCommercial 4.0 International License.
